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GCSE AQA Biology


Master GCSE AQA Biology with our interactive study cards designed for effective learning. These flashcards use proven spaced repetition techniques to help you memorize key concepts, definitions, and facts. Perfect for students, professionals, and lifelong learners seeking to improve knowledge retention and ace exams through active recall practice.


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What is a cell?

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Answer:

The basic structural and functional unit of all living organisms.

What are the parts found in both animal and plant cells?

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Answer:

Cell membrane nucleus cytoplasm mitochondria and ribosomes.

What structures are found in plant cells but not animal cells?

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Answer:

Cell wall vacuole and chloroplasts.

What is the function of the nucleus?

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Answer:

It contains the genetic material (DNA) and controls the activities of the cell.

What is the function of the mitochondria?

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Answer:

The site of aerobic respiration where energy (ATP) is released.

What is the function of the ribosomes?

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Answer:

The site of protein synthesis.

What is the function of the cell membrane?

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Answer:

Controls what substances enter and leave the cell.

What is the function of the chloroplast?

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Answer:

The site of photosynthesis where light energy is absorbed by chlorophyll.

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What is the function of the cell wall in plant cells?

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Answer:

Provides structural support and shape to the cell. Made of cellulose.

What is the function of the vacuole in plant cells?

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Answer:

Contains cell sap and helps maintain turgor pressure to keep the cell firm.

What is a prokaryotic cell?

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Answer:

A cell with no membrane-bound nucleus. DNA floats freely in the cytoplasm. Example: bacteria.

What is a eukaryotic cell?

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Answer:

A cell with a true membrane-bound nucleus. Examples: plant and animal cells.

What is diffusion?

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Answer:

The net movement of particles from an area of high concentration to an area of low concentration down a concentration gradient.

What is osmosis?

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Answer:

The movement of water molecules through a partially permeable membrane from a region of high water potential to a region of low water potential.

What is active transport?

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Answer:

The movement of substances against a concentration gradient using energy from respiration.

What is the equation for magnification?

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Answer:

Magnification = image size divided by actual size

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What are stem cells?

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Answer:

Undifferentiated cells that can divide and differentiate into specialised cell types.

What is differentiation?

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Answer:

The process by which a cell becomes specialised for a particular function.

What are the products of mitosis?

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Answer:

Two genetically identical diploid daughter cells.

What is mitosis used for?

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Answer:

Growth repair and asexual reproduction.

What is the word equation for aerobic respiration?

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Answer:

Glucose + oxygen → carbon dioxide + water (+ energy)

What is the word equation for anaerobic respiration in animals?

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Answer:

Glucose → lactic acid (+ energy)

What is the word equation for anaerobic respiration in plants and yeast?

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Answer:

Glucose → ethanol + carbon dioxide (+ energy)

What is fermentation?

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Answer:

Anaerobic respiration in yeast producing ethanol and carbon dioxide.

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What is the word equation for photosynthesis?

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Answer:

Carbon dioxide + water → glucose + oxygen (using light energy)

What factor limits photosynthesis on a cold cloudy day?

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Answer:

Both low light intensity and low temperature.

What is the role of chlorophyll in photosynthesis?

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Answer:

It absorbs light energy (mainly red and blue wavelengths) to power the reaction.

Where does photosynthesis take place?

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Answer:

In the chloroplasts mainly in the mesophyll cells of leaves.

What are the three limiting factors of photosynthesis?

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Answer:

Light intensity carbon dioxide concentration and temperature.

What is the function of stomata?

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To allow gas exchange (CO2 in O2 out) and water vapour to leave the leaf.

What is transpiration?

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Answer:

The loss of water vapour from the leaves of a plant through the stomata.

What is the function of xylem?

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Answer:

To transport water and dissolved minerals from the roots up to the leaves.

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What is the function of phloem?

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Answer:

To transport dissolved sugars (sucrose) from the leaves to the rest of the plant (translocation).

What is the test for starch?

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Answer:

Add iodine solution — it turns blue-black in the presence of starch.

What is the test for glucose?

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Answer:

Add Benedict's solution and heat — it turns from blue to brick-red/orange if glucose is present.

What is the test for protein?

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Answer:

Add biuret reagent — it turns from blue to purple/violet in the presence of protein.

What is the test for lipids?

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Answer:

Add ethanol then water — a white milky emulsion forms if lipids are present.

What is the function of enzymes?

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Answer:

Biological catalysts that speed up chemical reactions in living organisms.

What is the active site of an enzyme?

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Answer:

The specific region where the substrate binds to form an enzyme-substrate complex.

What is the lock and key model of enzyme action?

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Answer:

The substrate fits exactly into the active site of the enzyme like a key fits a lock.

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What happens to an enzyme at very high temperatures?

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Answer:

It denatures — the active site changes shape so the substrate can no longer bind.

What is the optimum pH for most enzymes in the human body?

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Answer:

Around pH 7 (neutral) though some like pepsin work best at acidic pH.

What enzyme digests starch?

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Answer:

Amylase (produced in the salivary glands and pancreas).

What enzyme digests proteins?

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Answer:

Proteases (e.g. pepsin produced in the stomach).

What enzyme digests lipids?

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Answer:

Lipase (produced in the pancreas).

What is the role of bile in digestion?

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Answer:

It emulsifies fats into smaller droplets increasing the surface area for lipase to act on.

Where is bile produced and where is it stored?

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Answer:

Produced in the liver and stored in the gall bladder.

What are the products of digestion of carbohydrates?

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Answer:

Glucose (simple sugars)

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What are the products of digestion of proteins?

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Answer:

Amino acids

What are the products of digestion of lipids?

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Answer:

Fatty acids and glycerol

What is the function of red blood cells?

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Answer:

To carry oxygen around the body using haemoglobin.

Why do red blood cells have no nucleus?

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Answer:

To make more room for haemoglobin to carry oxygen.

What is the function of white blood cells?

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Answer:

To defend the body against infection by ingesting pathogens or producing antibodies.

What is the function of platelets?

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Answer:

To help blood clot at a wound to prevent blood loss and infection.

What is the function of plasma?

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Answer:

The liquid component of blood that transports dissolved substances including glucose CO2 hormones and urea.

What is the role of haemoglobin?

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Answer:

It binds to oxygen in the lungs to form oxyhaemoglobin and releases it at the tissues.

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What is the difference between arteries and veins?

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Answer:

Arteries carry blood away from the heart under high pressure with thick muscular walls. Veins carry blood to the heart under low pressure and have valves.

What is the function of capillaries?

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To allow exchange of substances between the blood and tissues due to their thin walls and large surface area.

What is coronary heart disease?

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Answer:

A condition where the coronary arteries become narrowed by fatty deposits (plaques) reducing blood flow to the heart muscle.

What are the four chambers of the heart?

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Answer:

Right atrium right ventricle left atrium and left ventricle.

What is the role of the left ventricle?

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Answer:

To pump oxygenated blood out to the body through the aorta. It has the thickest muscular wall.

What are pathogens?

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Answer:

Microorganisms that cause infectious disease. They include bacteria viruses fungi and protists.

How do bacteria cause disease?

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Answer:

They reproduce rapidly inside the body and produce toxins that damage tissues.

How do viruses cause disease?

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Answer:

They invade cells and use the cell's machinery to reproduce then burst out destroying the cell.

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What is an example of a disease caused by a virus?

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Answer:

Measles influenza HIV or COVID-19.

What is an example of a disease caused by bacteria?

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Answer:

Salmonella food poisoning or tuberculosis (TB).

What is an example of a disease caused by a protist?

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Answer:

Malaria (caused by Plasmodium spread by mosquitoes).

What is the role of antibodies?

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Answer:

Proteins produced by white blood cells (lymphocytes) that bind to specific antigens on pathogens and neutralise or destroy them.

What is the difference between active and passive immunity?

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Answer:

Active immunity involves the body producing its own antibodies (after infection or vaccination). Passive immunity involves receiving antibodies from another source (e.g. mother's milk or injection).

How do vaccines work?

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Answer:

They introduce a weakened or dead pathogen (or its antigens) to stimulate the immune system to produce antibodies and memory cells without causing disease.

What are antibiotics?

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Answer:

Medicines that kill or inhibit the growth of bacteria. They do not work against viruses.

Why is antibiotic resistance a growing problem?

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Answer:

Bacteria evolve resistance through natural selection and overuse of antibiotics speeds up this process making infections harder to treat.

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What is the nervous system composed of?

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Answer:

The brain spinal cord and a network of nerves (neurons).

What is a reflex action?

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Answer:

A rapid automatic response to a stimulus that does not involve conscious thought from the brain.

What is the pathway of a reflex arc?

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Answer:

Stimulus → receptor → sensory neuron → relay neuron (in spinal cord) → motor neuron → effector → response

What are the two types of effectors?

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Answer:

Muscles (which contract) and glands (which secrete hormones or other substances).

What is a synapse?

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Answer:

A junction between two neurons where a chemical neurotransmitter diffuses across a small gap to transmit the nerve signal.

What is the role of the hormone insulin?

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Answer:

It is produced by the pancreas and causes cells to take up glucose from the blood lowering blood glucose levels.

What is the role of glucagon?

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Answer:

It is produced by the pancreas and causes the liver to convert glycogen back into glucose raising blood glucose levels.

What is type 1 diabetes?

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Answer:

A condition where the pancreas does not produce enough insulin. It is treated with insulin injections.

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What is type 2 diabetes?

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Answer:

A condition where body cells stop responding to insulin. It is linked to obesity and treated with diet and exercise.

What is ADH and what does it do?

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Answer:

Anti-diuretic hormone produced by the pituitary gland. It controls water reabsorption in the kidneys.

What is the role of FSH in the menstrual cycle?

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Answer:

Follicle-stimulating hormone causes an egg to mature in the ovary and stimulates oestrogen production.

What is the role of oestrogen in the menstrual cycle?

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Answer:

It repairs the uterus lining after menstruation and triggers a surge of LH which causes ovulation.

What is DNA?

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Answer:

A double-stranded molecule made of nucleotides arranged in a double helix that carries genetic information.

What is a gene?

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Answer:

A section of DNA that codes for a specific protein.

What are the four bases in DNA?

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Answer:

Adenine (A) thymine (T) cytosine (C) and guanine (G).

What are the base pairing rules in DNA?

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Answer:

A pairs with T and C pairs with G.

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What is a chromosome?

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Answer:

A long coiled molecule of DNA found in the nucleus of a cell.

How many chromosomes do human body cells contain?

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Answer:

46 (23 pairs)

What is the difference between a dominant and recessive allele?

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Answer:

A dominant allele is expressed even if only one copy is present. A recessive allele is only expressed if two copies are present.

What is a genotype?

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Answer:

The genetic makeup of an organism (the alleles it carries).

What is a phenotype?

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Answer:

The observable characteristics of an organism resulting from its genotype and environment.

What is a homozygous organism?

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Answer:

An organism with two identical alleles for a particular gene (e.g. BB or bb).

What is a heterozygous organism?

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Answer:

An organism with two different alleles for a particular gene (e.g. Bb).

What is natural selection?

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Answer:

The process by which organisms with advantageous traits are more likely to survive reproduce and pass on their genes.

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What is evolution?

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Answer:

The gradual change in the inherited characteristics of a population over many generations.

What is extinction?

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When all members of a species have died and the species no longer exists.

What are the levels of organisation in an ecosystem?

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Individual → population → community → ecosystem

What is a food chain?

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Answer:

A sequence showing the feeding relationships between organisms with arrows showing the direction of energy flow.

What is a producer?

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An organism (usually a plant) that makes its own food through photosynthesis forming the base of a food chain.

What is a consumer?

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Answer:

An organism that obtains energy by eating other organisms.

What is biodiversity?

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Answer:

The variety of different species and the genetic variation within species in an ecosystem.

What is the carbon cycle?

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Answer:

The continuous process by which carbon is recycled through living organisms and the environment via photosynthesis respiration decomposition and combustion.

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